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I brush my teeth twice a day--one in the morning and before bed. I hate the notion of having food in mouth while I sleep. I used to brush my teeth once a day and it was problematic. This may be too much information but when I would brush my teeth once a day, I would find left over food in my mouth from the night before. It was absolutely disgusting. I think that I am going to start brushing after every meal to ensure that there aren't any foods left in my mouth. I wouldn't want the bacteria to cause an infection like it has before. Having pain in your mouth is the worst pain I have ever endured.